calciumchannel相关论文
钙稳态失衡和自噬异常是PD、AD及肌萎缩侧索硬化症(ALS)等神经退行性疾病的重要发病机制，二者之间存在相关性。研究显示，细胞不同储......
Hydrogen sulfide-induced enhancement of gastric fundus smooth muscle tone mediated by Voltage-depend
Objectives:Hydrogen sulfide (H2S) has been proposed as a gasotransmitter similar to nitric oxide (NO) and carbon monoxid......
Objective Rattin,a specific derivative of humanin in rats,can protect against amyloid β(Aβ)peptide-induced deficits in......
Autism spectrum disorder(ASD)is a group of neurodevelopmental disorders with a strong genetic component.Many lines of ev......
Objective Autism spectrum disorders(ASD)are a group of neurodevelopmental disorders.The pathogenetic mechanism of ASD re......
Transient Receptor Potential Canonical (TRPC) proteins assemble to form channels that enable influx of calcium and sodiu......
Calmodulin-and Ca2+-dependent facilitation and inactivation of the CaV1.2 Ca2+ channels in guinea-pi
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Chronic heart failure is a complex clinical syndrome with impaired myocardial contractility.Failing cardiomyocytes exhib......
Since the discovery of mammalian TRPC family in 1995, various physiological functions of the Ca2+-permeable TRPC channel......
Long-term effects of imidapril on calcium and potassium currents in rabbit left ventricular hypertro
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The beta-adrenergic blocker carvedilol restores L-type calcium current in a myocardial infarction mo
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Calcium channels at the center of nucleotide-binding leucine-rich repeat receptor-mediated plant imm
Higher plants utilize a variety of immune receptors to recognize pathogens and trigger defense responses.Intracellular n......
Mitochondrial calcium uptake plays a critical role in various cellular functions.After half a century of extensive s......
Neuroligins (Nlgs),the neural adhesion molecules,are thought to be required in synaptogenesis and functions via bind......
Voltage-gated calcium channels (VGCCs) are crucial for numerous physiological processes.Their activity is tightly regula......
目的探讨L型钙离子通道α1C亚基(calcium channel，voltage-dependent，L type，alpha 1C subunit，CACNA1C)基因多态性与精神分裂症的关联......
OBJECTIVE: To review the relationship between calcium ion channel and epilepsy for well investigating the pathogenesis o......
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Adenosine modulates diverse physiological and pathological processes in the brain, including neuronal activities, blood ......
Ligustrazine inhibits high voltage-gated Ca2+ and TTX-resistant Na+ channels of primary sensory neur
Objective Ligustrazine, also named as tetramethylpyrazine, is a compound purified from Ligusticum chuanxiong hort and ha......
AIM: Increasing evidence indicates that inflammation contributes to the initiation and perpetuation of atrial fibrillati......
脑缺血/再灌注损伤主要与自由基过度形成、兴奋性氨基酸毒性作用、炎性反应、细胞内Ca2超载及细胞凋亡等密切相关,其中Ca2超载及其......
转移是恶性肿瘤治疗困难的重要因素之一.肿瘤细胞中,钙库操纵性钙内流(SOCE)及其主要组成分子STIM1和Orai1参与包括细胞迁移、侵袭......
目的研究短周期动态压应力对体外培养的大鼠生长板软骨细胞Sox9、Ⅱ型胶原mRNA及蛋白表达水平的影响，探讨L-型钙离子通道是否参与该......
目的观察葡萄糖对豚鼠心室肌细胞膜APD,IK1,IK,ICa-L的影响.方法采用全细胞膜片技术记录单个豚鼠心室肌细胞膜的动作电位时程和离......
AIM: To study the anti-neoplastic effect of Haimiding and its mechanisms of action.METHODS: Experiments using MTT and co......
Background:Cerebrovascular disease(CVS)is one of the major complications of subarachnoid hemorrhage(SAH) and the major c......
目的 观察体外小儿骨髓间充质干细胞(MSCs)对周期性牵张应力的早期应答反应.方法 分离并培养小儿MSCs,利用体外细胞牵张应力装置对......
目的 探讨脊髓损伤(SCI)后逼尿肌细胞钙通道改变及其与逼尿肌反射亢进(DH)的关系.方法 建立SD大鼠骶髓上损伤动物模型,进行逼尿肌......
目的：观察野罂粟总生物碱中八种翻天复地碱单体心血管应的构效关系。：采用离体实验观察单体对ＫＣＬ所致兔胸主动脉环收缩的影响，并以Ｖｅｒ作对照......
目的：观察药物水飞蓟宾对分离的成年大鼠心肌细胞钙通道阻滞效应。方法：用成年大鼠分离的心肌细胞，以放射性同位素＾４５Ｃａ＾２＋作示踪，通过对经细胞......
目的：研究花椒挥发油（EOZM）对离体未孕雌激素预处理小白鼠子宫平滑肌的作用及其可能的机制。方法：分别观察EOZM和维拉帕米（Vet）对催产素（O......
AIM To investigate the effect of gingerol on colonicmotility and the action of L-type calcium channelcurrents in this pr......
